Pharmaceuticals

Pfizer acquires the rights to the Chinese biotech 3Sbio for 1.25 billion

The Chinese company's stock is up 32% in Hong Kong and brings the balance since the beginning of the year to a positive 221%.

by Mo.D.

FILE PHOTO: The Pfizer logo is seen on the pharmaceutical company's manufacturing plant, in Newbridge, Ireland February 10, 2025. REUTERS/Clodagh Kilcoyne/File Photo

2' min read

2' min read

Pfizer is investing $1.25 billion in a Chinese biotech. The US group obtained the rights to 3SBio's oncology drug by awarding the eponymous company an initial payment of $1.25 billion and a further potential $4.8 billion depending on the results that will be achieved in the next phase of trials.

The terms of the agreement

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The agreement grants Pfizer exclusive rights to develop and market the experimental drug, which is currently in the clinical phase for several types of cancer. The amount paid for the early phase represents a record for an outbound licensing agreement from China, and 3SBio, a Shenyang-based company, will be able to collect up to 4.8 billion in performance milestone payments upon achievement of all clinical and regulatory milestones. 3SBio plans to launch its first late-stage study in China within the year. Although Pfizer has not yet disclosed its clinical programme, it has announced that production of the active ingredient will take place in the US.

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In addition to licensing, Pfizer will make a $100 million equity investment in 3SBio, which is listed in Hong Kong and is active in the sale of therapies for oncology, autoimmune diseases, renal failure, dermatology and other segments.

Market reactions

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The news led to buying on 3SBio stock surged as much as 52% in Hong Kong, the largest gain recorded in a single day, continuing for the third consecutive session in positive territory. It was up +32.28% at the close, bringing the balance since the start of the year to +221.27%. Pfizer's stock traded in positive territory by about 2% on Wall Street.

The deal then drove the healthcare sector: the prices of ApicHope Pharmaceutical Group and Zhejiang Huahai Pharmaceutical hit daily highs of 20% and 10% respectively on the Chinese onshore market. Within the Hang Seng Composite Index, the healthcare sub-index was the best performer, rising by up to 3.8%. On the Hong Kong Stock Exchange, CSPC Pharmaceutical Group and Innovent Biologics also closed up 9.6% and 8.9%, respectively.

The China Bet

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Over the past twelve months, many large pharma groups have set their sights on Chinese-originated research molecules in an attempt to bolster their pipeline. In 2024, the number of licensing deals from Chinese companies hit an all-time high, with 28% of new innovative drugs licensed from Chinese biotechs, according to GlobalData.

Even in 2025, the trend did not stop: Novo Nordisk and Merck both spent USD 200 million upfront on an anti-obesity drug and a cardiometabolic treatment, respectively.

With this deal, Pfizer joins a small club of challengers to Merck's blockbuster drug Keytruda: 3SBio's candidate acts on the same target as a therapy developed by Akeso, which outperformed Keytruda in a study. Merck in turn acquired a similar compound from LaNova Medicines.

Pfizer, which had previously entered into a research agreement with Summit Therapeutics - Akeso's partner in the US - to test combinations of molecules, confirmed that this collaboration will not be affected by the new licensing.

According to Citigroup analysts, the new deal may alleviate investor concerns about geopolitical risks related to out-licensing, which has enhanced the value of Chinese biotechs. "Global expansion remains the main driver for innovative pharma/biotech stocks," they note, to the point of raising 3SBio's target price from HK$13 to HK$21.

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