Pharmaceuticals

Sanofi acquires Blueprint for $9.1 billion

The agreement provides for a payment to the biotech's shareholders of $129 per share, a 27% premium over Friday's closing price

by Mo.D.

2' min read

2' min read

The shopping spree of the big international pharmaceutical groups continues. The latest deal announced is Sanofi's acquisition of Blueprint Medicines for a total equity value of $9.1 billion. The deal is part of the French group's strategy to expand its drug portfolio dedicated to rare immunological diseases.

In PArigi, Sanofi's stock trades down less than half a percentage point, while Wall Street trading is expected to open for the US biotech. In pre-market trading, it gained more than 26 per cent in line with the offer price.

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The details of the acquisition

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The deal calls for a cash consideration of $129 per share, representing a 27% premium over Blueprint's closing share price on Friday. Shareholders of the US biotech will also receive a non-negotiable contingent value right (CVR), which could yield an additional $2 or $4 per share upon the achievement of certain regulatory and clinical development milestones related to BLU-808, an investigational therapy for mast cell disorders, including chronic urticaria.

Including potential CVR-related payments, the transaction reaches a total value of approximately USD 9.5 billion on a fully diluted basis. Sanofi expects to finalise the acquisition in the third quarter of 2025 and has indicated that the transaction will not significantly affect its financial outlook for the year.

Sanofi's expansion strategy

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The acquisition is part of Sanofi's broader goal to establish itself as a leader in immunology. Earlier this year, the French group had already signed a $1.9 billion deal with Dren Bio to acquire a drug against autoimmune diseases. Regarding this latest deal, Sanofi emphasises that the acquisition of Blueprint brings with it a promising pipeline of immunological drugs under development and a strong network of relationships with specialists in the field.

But the strategy of expansion by external lines looks set to continue in the near future since CEO Paul Hudson stated in the release: 'Sanofi still has significant capacity for further M& A operations.

Blueprint's business

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Blueprint currently markets Ayvakit (Ayvakyt in Europe), a treatment for systemic mastocytosis, a rare condition characterised by an abnormal accumulation of mast cells, which can cause debilitating symptoms such as hives, abdominal pain and anaemia. According to company forecasts, the drug will generate$700 to $720 million in revenues in 2025.

The acquisition represents the culmination of a strategic transformation for Blueprint, founded in 2008 and listed since 2015, which initially focused on oncology. After the end of its collaboration with Roche and the withdrawal of an approved oncology drug from the market, the company chose to refocus on immunological diseases.

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