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Cancer, declining EU mortality and positive data for lung in women: estimates for 2026

Forecasts published in Annals of Oncology and coordinated by the Università Statale di Milano show a reversal of the trend: after more than 25 years of increase, lung cancer mortality rates among women in EU countries show a stabilising trend with approximately -5% over the three-year period 2020-2022

by Health Review

4' min read

Translated by AI
Versione italiana

4' min read

Translated by AI
Versione italiana

According to new estimates, around 1,230,000 cancer deaths will occur in the European Union in 2026, with a mortality rate of 114 per 100,000 men (-7.8% compared to 2020-2022) and 74.7 per 100,000 women (-5.9%). Forecasts are positive, particularly for lung cancer in women, with mortality rates stabilising at around 12.5 deaths per 100,000 (-5% compared to 2020-2022). The results of the study estimating cancer mortality rates in the EU and the UK for 2026, coordinated by the State University of Milan in collaboration with the University of Bologna and the University of Parma and supported by the Airc Foundation for Cancer Research, were published in the Annals of Oncology. After more than 25 years of increase, lung cancer mortality rates among women in European Union (EU) countries are now showing a stabilising trend, while in the UK such favourable trends have been observed for several years, although overall female mortality levels are still higher than the EU average.

 The study

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The researchers, co-ordinated by Professor Carlo La Vecchia, Professor of Medical Statistics and Epidemiology at the State University of Milan, and Professor Eva Negri, Professor of Environmental Epidemiology and Occupational Medicine at the University of Bologna, analysed, for the sixteenth consecutive year, cancer mortality rates since 1970 considering the 27 EU Member States as a whole and, separately, the United Kingdom, using data from the World Health Organisation and United Nations databases. For each country and for both sexes, the following types of cancer were examined: stomach, colorectal, pancreas, lung, breast, uterus (including cervix), ovary, prostate, bladder and leukaemia, with a particular focus on lung cancer.

The focus on the lung

For the latter, the improvement in women will affect women up to 64 years of age, while in the older age groups mortality rates are still increasing.

"Lung cancer remains the leading cause of cancer death in both sexes in the EU. Mortality rates continue to decline among men, while remaining almost double those observed in women in 2026. This trend is consistent with historical differences in tobacco consumption behaviour between men and women,' said Claudia Santucci, researcher at the State University of Milan and first author of the article. In most of the countries considered, previous upward trends among women seem to be stabilising, with the exception of Spain. In the US and the UK, women started smoking earlier than European women, but also quit earlier. Currently, smoking prevalence in both sexes is less than 10% in the US and the UK, while it remains higher in the EU. In particular, Spanish and French women started smoking later than those in other EU countries, but also quit later. The same is true for Italian women, but they have always smoked less'.

The overview

It is estimated that in 2026 there will be about 1,230,000 deaths from all cancers in the EU, corresponding to an age-standardised mortality rate of 114 per 100,000 men (-7.8% compared to 2020-2022) and 74.7 per 100,000 women (-5.9%).
The mortality forecasts for the different cancer sites analysed are favourable in most countries, with the exception of female deaths from pancreatic cancer in the EU (up 1%) and female deaths from colorectal cancer in the UK (up 3.7%).

"We estimate that a total of about 7.3 million cancer deaths have been avoided in the EU and 1.5 million in the UK since the peak in 1988, assuming mortality rates had remained constant at 1988 levels. Among men, approximately 1.8 million deaths from lung cancer were avoided during this period, while among women, no deaths avoided from this cancer were observed,' explained Professor Eva Negri.

Professor of medical statistics and epidemiology at the University of Parma co-author of the research, Matteo Malvezzi, adds: 'In contrast to the major EU countries, colorectal cancer mortality is increasing in young adults in the UK, probably due to increased prevalence of overweight, obesity and consequently diabetes.

However, the ageing population will lead to a modest increase in the absolute number of deaths: among men in the EU it will rise from 666,924 (2020-2022) to about 684,600 in 2026, and among women from 534,988 to about 544,900. In the UK, by contrast, deaths will remain stable: about 91,400 in men and 80,500 in women in 2026.

Prevention starting with smoking

"Our results underline the continuing importance of smoking in cancer mortality. Tobacco control remains the cornerstone of lung cancer prevention and also contributes to the prevention of other cancers, such as pancreatic cancer. Policies to limit tobacco use have prevented millions of smoking-related deaths, but their implementation remains uneven across Europe. Overall, cancer mortality rates remain generally favourable and pancreatic cancer mortality appears to have stabilised, which is encouraging after previous increases. This probably reflects improvements in the reduction of occupational and environmental exposures to carcinogens. Disparities in cancer mortality rates also persist between the countries analysed and the sexes. In several countries, in addition to delays in tobacco control, cancer screening programmes, diagnosis and management can and should be improved to align with recent progress, especially in Central and Eastern European countries,' Professor Carlo La Vecchia concluded.

The authors finally emphasise that strengthening tobacco taxation, introducing advertising bans, expanding smoke-free spaces and enhancing cessation support services are key measures to reduce regional and socio-economic inequalities and achieve a sustained reduction in cancer mortality in Europe. In addition, controlling overweight and obesity, improving eating habits, reducing alcohol consumption and enhancing screening programmes for early detection of cervical, breast and colorectal cancers remain key strategies in cancer prevention.

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