Addictions

Smoking whilst living with a serious illness: when cutting down is already part of the treatment

The reorganisation of local healthcare services must strengthen the SerD and anti-smoking centres, creating integrated, interdisciplinary networks and facilities offering direct access, such as community centres

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3' min read

Translated by AI
Versione italiana

3' min read

Translated by AI
Versione italiana

When smoking is associated with a serious illness, simply asking the patient to give up is not enough. Tobacco use disorder is a complex, multifactorial addiction, underpinned by neurobiological, behavioural and environmental mechanisms common to other addictions. Management is the responsibility of addiction specialists (SerD), who work within multi-professional teams and integrate medical, psychological, nursing, educational and social expertise. Treatment is more effective when carried out in collaboration with psychiatrists, pulmonologists, oncologists, cardiologists and other specialists involved in the management of comorbid conditions.

A recent survey by FeDerSerD involved 162 smoking cessation centres: around 80 per cent are part of the SerD network. The survey confirms the central role of addiction services, but also reveals a network that remains uneven in terms of staffing levels, accessibility and integration with hospitals, general practice and mental health services.

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A bridge towards abstention

Complete cessation remains the therapeutic goal. However, in patients with severe addiction associated with psychiatric disorders, chronic lung diseases, cardiovascular conditions or cancer, this may not be immediately achievable. Controlled reduction therefore serves as a stepping stone towards abstinence: it reduces exposure to toxic combustion by-products and the intake of nicotine, a psychoactive substance that is highly addictive.

Reducing one’s intake means addressing the intensity of the addiction. Chronic exposure to nicotine leads to tolerance and neuroadaptations in the reward and withdrawal circuits. A gradual, supported reduction can make cravings (the compulsive desire to use) and withdrawal symptoms more manageable, help establish a state of lower addiction intensity, and pave the way for complete cessation. It is not an end in itself, but a stage in the overall treatment plan, involving motivational and pharmacological interventions, as well as regular reassessments.

Prejudices in psychiatric disorders

Psychiatric comorbidity requires particular attention. In psychotic, depressive and anxiety disorders, addiction is often more severe and cessation rates are lower. Prejudices persist: that smoking is secondary to mental illness, that abstinence exacerbates it, or that nicotine acts as a form of self-medication. Diagnostic assessment, progressive goals and integration between drug treatment services and psychiatric services are required.

Every step must strike a balance between the risks and benefits. The benefit of reduction or discontinuation must be balanced against the risk of clinical destabilisation, poor adherence or uncontrolled changes to medication. Clinical monitoring and dose adjustments allow psychological stability to be maintained whilst progressing towards abstinence.

In cancer and respiratory disease patients, a diagnosis can lead to fear, depression and fatalism. Smoking, which has long been associated with immediate relief, may become more frequent precisely when it would be most necessary to give it up. Cancer patients often feel that “it doesn’t matter anymore”; in patients with lung disease, denial of the role of smoking may prevail. Blaming the patient is ineffective: the focus must be on mood, motivation, confidence and tangible benefits. In oncology, giving up smoking even after a cancer diagnosis improves the prognosis, reduces surgical complications and can increase the effectiveness of treatments: this is why smoking cessation is referred to as the ‘fourth pillar’ of care.

How to deal with relapses

Why is it so difficult to quit in these cases? Resistance operates on three levels: biological, psychological and contextual, involving the severity of the addiction, mood, habitual behaviours, relationships and access to services. A relapse does not equate to a lack of willpower, but signals a need for more intensive care, which requires the involvement of various specialists.

Today, the treatment of tobacco use is often excluded from care pathways for chronic conditions. However, every consultation in which the issue is not addressed represents a missed therapeutic opportunity. FeDerSerD believes that the diagnosis and treatment of tobacco use disorder must be permanently incorporated into the Essential Levels of Care and the Diagnostic-Therapeutic Care Pathways, thereby strengthening the link between hospitals, local communities, general practice and addiction services.

Against this backdrop, a paradoxical and contradictory reality emerges: the ways in which tobacco and nicotine are consumed, and the products themselves, are evolving more rapidly than therapeutic responses. The industry is innovating devices and strategies, whilst services are struggling to develop integrated, accessible and continuous care pathways at the same pace. The reorganisation of local healthcare services can bridge this gap by strengthening Substance Abuse Services (SerD) and Smoking Cessation Centres, and by creating integrated, interdisciplinary networks and facilities with direct access, such as community centres. Reduction and cessation are not conflicting therapeutic goals: in the most complex cases, the former may be the most realistic pathway towards the latter.

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*FeDerSerD President

Contributors:

Vincenzo Verardi: Medical Pharmacologist – Head of Healthcare, Inpatient Substance Use Disorders Service, Department of Pathological Addictions – Taranto Local Health Authority;

Giulia Audino: Physician, Pharmacologist and Clinical Toxicologist – Director of SerD – President of FeDerSerD Calabria;

Concettina Varango: Physician, Pharmacologist and Clinical Toxicologist – Director of the Addiction Unit at ASST Pavia;

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