Medicine

Your heart is at risk if you go to bed at different times: just 29 minutes can make all the difference

Getting eight hours’ sleep a night might not be enough. Because, as well as the quantity and quality of sleep, there is a third factor that should not be underestimated: regularity

Alarm clock on night table showing 3 a.m. Photographee.eu - stock.adobe.com

4' min read

Translated by AI
Versione italiana

4' min read

Translated by AI
Versione italiana

Sleep can be a panacea, but it can also be a risk factor for cardiovascular disease and metabolic disorders (particularly diabetes and obesity). However, it is not just how much we sleep, or the structure and quality of our sleep, that matters. The time at which we turn off the light each evening is also crucial. A study covering over a million nights, due to be presented in the coming days at the American Heart Association’s conference, has found a link between going to bed at different times each night and an increased risk of heart attack, stroke and heart failure.

Sleeping eight hours a night may therefore not be enough to protect the heart. This is because, in addition to the quantity and quality of sleep, there is a third factor that should not be underestimated: the regularity with which we close our eyes each evening to drift off into the arms of Morpheus. Going to bed at a different time every evening, indulging in long sleeps at the weekend under the illusion of making up for lost sleep during the week, or alternating between nights of short sleep and very long ones could have consequences for cardiovascular health. What’s more, even seemingly insignificant variations can make a difference: every 29-minute increase in the irregularity of sleep duration results in a 24 per cent increase in the risk of cardiovascular events.

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This is suggested by a study carried out by researchers at Boston Children’s Hospital and Harvard Medical School, which will be presented at the American Heart Association’s Scientific Sessions 2026, due to take place in Chicago from 7 to 9 November.

The Stars and Stripes Sleep Study

American researchers have analysed over a million nights’ sleep from 10,362 adults, with an average age of 53, who were monitored using wearable devices as part of the ‘All of Us’ Research Programme run by the US National Institutes of Health . Over a period of approximately six months, the researchers analysed not only the hours spent sleeping, but also the times at which participants fell asleep and woke up (sleep regularity), the quality of sleep (i.e. how much of the night was spent in REM, light or deep sleep, and how long a person remained awake after first falling asleep), the number of sleep cycles completed each night and the duration of each cycle. The participants, who were in good health at baseline and had no cardiovascular or metabolic diseases, were followed for a median of 3.7 years.

Turning off the light at different times each evening increases the risk of heart problems

The findings of this research should serve as a wake-up call for those with particularly irregular sleeping patterns. Variations in sleep times from one night to the next were found to be associated with a 20–23 per cent increase in the risk of serious cardiovascular events, such as heart attacks, strokes and heart failure. Every 29-minute increase in the variability of sleep duration was associated with a 24 per cent increase in overall cardiovascular risk, a 29 per cent increase in heart muscle disease and a 20 per cent increase in heart failure.

But that’s not all. A higher number of complete sleep cycles was found to be associated with a 28 per cent reduction in the risk of atrial arrhythmias, whilst unusually long cycles were linked to a 55 per cent increase in the risk of a heart attack or stroke.

“We often focus on the importance of getting eight hours’ sleep every night; but in reality, maintaining regular bedtimes and wake-up times is a healthy habit that could help protect the heart and blood vessels,” explains Nguyen Minh Tuan Viet, a neuroscientist at Harvard Medical School and lead author of the study.

It is mainly weekend habits that come under scrutiny, when people tend to stay up late and allow themselves a few extra hours’ sleep in the morning, throwing their biological rhythms out of kilter. The situation is even more complex for shift workers, who experience a completely irregular sleep-wake cycle due to the nature of their work. “Sometimes the quality of our sleep is something beyond our control,” admits Viet. “But maintaining a regular sleep schedule – that is, going to bed at roughly the same time every night throughout the week and waking up at the same time every morning – is something many people can work on.”

Exercise caution regarding the results, but make the most of the advice that emerges from the research

The study presented at the AHA, whilst statistically significant, is observational in nature, and its findings should not be taken at face value. In other words, it is not necessarily the case that changing the duration of sleep by half an hour will definitely lead to an increased cardiovascular risk. Furthermore, the 29 minutes should be understood as the average of the usual variation over a six-month period, rather than as a single, occasional delay in going to bed.

But the message that emerges from this research is nonetheless interesting: getting enough sleep may not be enough to look after your heart. It also seems to be very important to do so regularly. And so, to incorporate cardiovascular prevention into your daily routine, it’s worth starting to keep an eye on the clock. Not just when the alarm goes off, but also when it’s time to switch off the light.

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