World Day / The interview

‘The heart: to protect it, we need screening programmes, just as we do for cancer’

Simple tests carried out as early as school age and close monitoring of risk factors ranging from cholesterol to diet and pollution: Giuseppe Patti, president-elect of the Italian Society of Cardiology, sets out the formula for truly effective prevention

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5' min read

Translated by AI
Versione italiana

5' min read

Translated by AI
Versione italiana

‘As many as one in six Italians suffers from cardiovascular disease, to the extent that 150,000 heart attacks are recorded in the country every year, whilst overall, a third of all deaths are attributable to cardiovascular causes. This is twice the number of deaths from cancer, although the perceived epidemiological, health and economic impact of heart disease is significantly lower, which explains why people are less motivated to engage in primary prevention and to follow treatment. Systematic screening should therefore be introduced, just as is done in oncology, where widespread testing saves millions of lives’. Giuseppe Patti, president-elect of the Italian Society of Cardiology (SIC), which he will take the helm of in 2029, is fully committed to implementing a preventive approach across ‘his’ Novara region, starting with schools. Originally from Calabria, he is currently a full professor of Cardiovascular Diseases at the Department of Translational Medicine and director of Cardiology and the Thoracic and Cardiovascular Department at the ‘Maggiore della Carità’ University Hospital in Novara.

What advice should be given, and from what age?

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The risk factors which, if present, increase the likelihood of having a heart attack or a stroke are well known, but we do not always bear them in mind. As many as half of these conditions can be attributed to the five most important and well-known risk factors: obesity, smoking, high blood pressure, high cholesterol and diabetes mellitus. Addressing these factors has a positive impact on all cardiovascular events. The other half consists of so-called lifestyle-related risk factors: for example, a lack of physical activity, whilst the recommendations state that the standard should be 20–30 minutes a day of moderate physical activity for at least 5 days a week. Dietary habits are also important; the Mediterranean diet, with its balanced content of fats, sugars, fruit and vegetables, offers ‘protection’, so much so that at least 200 grams of fruit or vegetables are recommended daily, along with 30 grams of nuts, which play a ‘protective’ role. Furthermore, there are other, decidedly underestimated non-traditional risk factors, such as alcohol consumption, which is a scourge on society: it should be remembered that a maximum of one glass of wine with a meal is acceptable for men and one per day for women.

From what age does all this start?

There is no specific age at which to ‘start’: cardiovascular prevention is a continuum that begins in the first thousand days of life. It begins as early as pregnancy; indeed, the expectant mother helps prevent cardiovascular disease in her child by managing gestational diabetes or high blood pressure. Another major problem is the rise in childhood obesity, and it is no coincidence that there is growing awareness of the negative impact of being overweight, even from early childhood. This is an issue that scientific societies should prioritise and address from school age onwards.

How much ‘weight’ do individual risk factors carry?

Traditional risk factors account for 50 per cent of the impact, whilst this figure rises to 90 per cent when we factor in a lack of physical activity, poor dietary habits and excessive alcohol consumption. The remaining 10–15 per cent is accounted for by so-called ‘new risk factors’, which are often overlooked but are extremely important, such as environmental pollution, chemical and microplastic pollution, night-time light pollution and noise pollution. Inflammatory diseases also have a harmful impact on our hearts. So does sleep deprivation: sleeping on average less than 6 hours a night increases cardiovascular risk, as do socio-economic difficulties, stress and social isolation.

According to the picture he paints, systematic prevention would significantly reduce cases and deaths...

Exactly. It is above all a question of mindset, a cultural issue. Half of all adults with high blood pressure are unaware of it, which is why it is important to get checked. To give another example, ‘cholesterol’ is often underestimated: not only is it dangerous to have high ‘LDL’, but the length of time one is exposed to this ‘bad’ cholesterol also plays a role. A European study published in the New England Journal of Medicine and presented in Munich a few weeks ago showed that one in 13 people under the age of 30 has atherosclerotic plaques in their arteries, both coronary and peripheral: it is important to start prevention at an early age.

How important is genetic predisposition?

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The idea is that if a person is genetically predisposed to heart disease, they must be even more rigorous in managing traditional risk factors. It would be very useful to carry out simple screening tests at school age, including amongst secondary school pupils and in any case by the age of 18: we are talking about a blood test, an electrocardiogram and a blood pressure reading. These are tests we have already carried out on several occasions in schools in Novara, to assess genetic risk, which is, of course, unchangeable.

Let us now turn to secondary prevention, once a cardiovascular event has already occurred

Poor adherence to treatment is a major factor here: on average, the longer the time since discharge, the lower a patient’s adherence to treatment tends to be. But it is not only the patient who loses motivation: doctors, too, often show a reluctance to prescribe certain medicines. This happens, for example, with statins, whose side effects occur very rarely – in fewer than 5 per cent of cases – whilst it must be emphasised that these medicines reduce the risk of death. It must be said that for the main risk factors – high blood pressure, high cholesterol and diabetes – we have very precise treatment targets that must be strictly adhered to in patients who have already suffered a heart attack. The higher a person’s risk, the more important it is to monitor these targets rigorously.

As the future president of SIC, what prevention strategies do you intend to promote?

The scientific society is already doing a great deal: cardiovascular prevention campaigns – which need to be rolled out across the population and in schools – awareness-raising campaigns to inform people about the impact in terms of both health and healthcare costs, and engagement with institutions. Screening must be promoted: breast, bowel and cervical cancer screening programmes in Italia are saving a great many lives; cardiovascular prevention should be extended to the entire population. We must also promote healthy lifestyles and tackle obesity. More generally, prevention should be integrated into all policies – both national and local – across the board and involving multiple ministries and stakeholders. To protect our hearts, we need a cultural revolution.

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