Infectious diseases

Measles doubling in one month: experts warn to vaccinate before the holidays

Focus by the Higher Institute of Health on the increase in cases also attributable to holiday travel. And on the papillomavirus, European experts met in Rome to relaunch coverage targets, which in Italy do not exceed 45%.

by Barbara Gobbi

(Adobe Stock)

3' min read

3' min read

From 37 cases in April to 65 reported in May: measles in one month "doubles" continuing the upward trend. Which is all the more worrying in view of the summer holidays. Because travel is one of the main vehicles, so much so that 20% of the 334 cases - almost 90% of which in unvaccinated people - reported since the beginning of 2025 have been associated with international travel, thanks to the many 'bridges' in this first half of the year, a figure that is up from 18% in the previous period.

Launching the warning to get vaccinated before leaving for the holidays is the Istituto Superiore di Sanità, in the light of the trends of recent months and the June bulletin on measles and rubella, which reports on the results of surveillance coordinated by the Department of Infectious Diseases of the Iss with the contribution of the national network of regional laboratories.

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Data and risks

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Vaccination status is known for 313 of the 334 cases reported in 2025, and in 275 cases (almost 90%) the affected persons were unvaccinated, explain the Iss. In about a third of the cases, 108, at least one complication was reported: among the most frequent were hepatitis or increased transaminases and pneumonia, but keratoconjunctivitis, diarrhoea, respiratory failure, stomatitis, thrombocytopenia, laryngotracheobronchitis, otitis, and convulsions also occurred. Three cases of encephalitis were reported, respectively in two adults and one pre-adolescent, all unvaccinated.

Children under 5 most affected

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The experts' appeal is therefore to 'check your measles vaccination status before embarking on any trip abroad. In fact, almost 80% of cases occur in people aged 15 years and over, most of whom are unvaccinated or have only had one dose. And children are also to be protected: the most affected age group, in terms of incidence, remains the under-fives, who are also particularly vulnerable to short- and long-term measles complications. But cases also continue to be reported among infants, for whom, as the experts point out, 'protection depends on a high level of immunity in the population, given that the recommended age for administration of the first dose of the Mpr vaccine is 12 months'.

Not only measles: focus on Hpv

Define a shared roadmap and manifesto to strengthen the fight against the papilloma virus (Hpv) in Europe, which still shows vaccination coverage far short of the 2030 WHO target of 90%, with figures in 2023 standing at 36% among 15-year-old girls and 24% among boys.

And Italy? In an extremely heterogeneous European panorama in which we range from peaks of 80-90% in Norway, Denmark, Portugal and the United Kingdom to the collapse to 10% in some Eastern European countries, our country is in the middle. This is according to data from the Ministry of Health: in 2023, vaccination coverage for Hpv among 12-year-olds stands at 45% for girls and 39% for boys. Among 15-year-olds, coverage rises to 70% for girls and 58% for boys, respectively. At the regional level, no region has yet reached the 95% target in all cohorts, and significant differences persist between geographical areas.

The Perch Project

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In the meantime, school vaccination has been introduced in three Italian regions, with coverage in the first municipalities involved reaching 90% for the first dose among girls and 87% among boys; for the full cycle 80% among females and about 70% among males. These are pilot experiences launched as part of the European Perch project, on which the next focus is expected on 13 June in Rome, where 18 countries have gathered at the Istituto Superiore di Sanità for the international conference 'EU4Health Projects on HPV: Final Results. What's the Next?" as part of the Partnership to Contrast Hpv. The idea is to 'stimulate the convergence of prevention strategies, encouraging mutual learning', emphasises Raffaella Bucciardini, scientific coordinator of the Perch project.

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