Iss surveillance

Measles: infections rise, one in three cases with hepatitis and pneumonia as complications

Last January 84 cases were recorded, 50 more than a year ago: the virus continues to circulate mainly among unvaccinated young adults

by Ernesto Diffidenti

3' min read

Translated by AI
Versione italiana

3' min read

Translated by AI
Versione italiana

The year 2026 opens with an increase in measles cases, including complications. The National Surveillance System of the National Institute of Health recorded 84 infections, up from 34 in the same month of 2025. Three of the reported cases (3.6 %) are imported and 2 related to imported cases. These numbers are small at the moment but indicate a clear trend. "After two years of high incidence of measles contagions in Italia, with 1,055 cases in 2024 and 532 in 2025, 2026 begins with a new increase in January," underline the experts from the Infectious Diseases Department of the Iss - "The virus continues to circulate in the country, especially among unvaccinated young adults.

96.4% of cases concentrated in six regions

Almost all cases (96.4%) came from only 6 regions (Lombardy, Tuscany, Lazio, Campania, Apulia and Calabria). The median age of the reported cases is 28 years, however the highest incidence is observed in the 0-4 years age group and 2 cases were reported in children under one year of age.

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"Vaccination status," explains the periodic newsletter Measles & Rubella News, "is known for 91.7 per cent of the cases, 90.9 per cent were unvaccinated at the time of infection. More than a third of the cases reported at least one complication: the most frequent were pneumonia and hepatitis/increased transaminases. Among the reported cases, five were health workers (of whom four were unvaccinated at the time of infection and one was vaccinated and had received two doses).

The European situation: almost 8 thousand cases and 8 deaths in 2025

In Europe, the Centre for Disease Prevention and Control (Ecdc) recently reported, between 1 January and 31 December 2025, 30 EU/EEA countries reported 7,655 measles cases and 8 deaths: 4 in France 3 in Romania and one in the Netherlands. "Although the total number of infections in 2025 represents a significant decrease from the more than 35,000 cases in 2024," the Iss points out, "it is almost double the number of cases reported in 2023. The highest reporting rates were observed in infants under one year of age (261.6 cases per million) and children aged between one and four years (127.4 cases per million).

79.9% of the cases were unvaccinated, 10.3% were vaccinated with one dose of measles vaccine, 7.9% were vaccinated with two doses and 1.7% were vaccinated with an unknown number of doses.

The World Health Organisation announced at the end of January 2026 that Armenia, Austria, Azerbaijan, Spain, the United Kingdom and Uzbekistan had re-established endemic transmission of measles based on the number of cases recorded in 2024.

But there is also alarm on the American continent. 'Measles cases are coming back to the world's attention,' says Massimo Ciccozzi, epidemiologist at the Campus Bio-Medico University: 'There are many countries that have outbreaks, and it seems that Mexico and the United States are already registering peaks of infections in the first month of 2026. In Mexico in particular, 9,500 cases and 31 deaths have been reported, so the situation is quite serious'.

How the infection is transmitted

Measles is a highly contagious viral disease that continues to circulate in Italia and, as mentioned, remains endemic in several other European countries, supported by insufficient vaccination coverage. It is transmitted by air (coughing and sneezing) and contagion occurs in 90% of cases among 'susceptible' people, i.e. those with reduced or absent immune defences. In Italia, measles vaccination coverage does not reach the 95% threshold suggested by the WHO for herd immunity and elimination of the virus, with declining rates (around 85-91% depending on doses and regions). The measles vaccine, administered as a combined MPR (measles-mumps-rubella) or MPRV (also for chickenpox), provides two doses for optimal protection of 99%. The first dose is recommended between 12-15 months of age, while the second dose, or booster, is generally administered at 5-6 years of age.

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