A Life Without Limits

Multiple sclerosis: the new challenge is to live better, with person-centred care based on research

From innovative treatments to rehabilitation, from physical activity to psychological wellbeing: these programmes look beyond the illness to meet patients’ needs

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4' min read

Translated by AI
Versione italiana

4' min read

Translated by AI
Versione italiana

It is no longer simply a matter of managing the disease, but of ensuring that people with multiple sclerosis can continue to live life to the full, nurturing relationships, interests and plans for the future. This is the new frontier in the treatment of a chronic, inflammatory and neurodegenerative neurological condition, the landscape of which has changed profoundly thanks to advances in research. The availability of increasingly effective treatments, together with improvements in early diagnosis and disease monitoring, has made it possible to reduce inflammatory activity and the risk of disability progression. Today, however, the ambition is broader: to preserve independence, wellbeing and quality of life over time.

Multiple sclerosis does not manifest itself in the same way in everyone, and its impact goes far beyond what is revealed by clinical examinations and MRI scans. Alongside the more obvious neurological symptoms, there may be less visible difficulties, such as fatigue, cognitive difficulties, sleep problems and mood changes, which profoundly affect daily life. This is why the effectiveness of a treatment programme must also be assessed in terms of its ability to meet individual needs and to preserve what each person considers essential to their own well-being.

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Research looks beyond inflammation control

The scope of research is broadening. Alongside the development of treatments capable of modulating the immune system and controlling inflammatory activity, there is a growing focus on the mechanisms responsible for the progression of disability and neurodegenerative damage. Neuroprotection and remyelination represent promising areas for developing strategies capable not only of preventing new lesions, but also of protecting nerve tissue and, in the long term, promoting its repair.

At the same time, the integration of biomarkers, advanced neuroimaging techniques and digital monitoring tools is paving the way for increasingly personalised medicine, with the aim of recognising early signs of disease progression and promptly adapting treatment strategies to individual characteristics.

An integrated approach: from physical activity to psychological wellbeing

The complexity of multiple sclerosis calls for a care model that goes beyond drug therapy. A multidisciplinary approach involving neurologists, physiatrists, physiotherapists, psychologists and neuropsychologists is essential for addressing the various aspects of the condition. In this context, neurorehabilitation can help to preserve motor, cognitive and functional abilities, thereby supporting independence and participation in everyday life.

Physical activity also plays an important role; when tailored to an individual’s circumstances, it can improve muscle strength, balance, mobility and endurance, with benefits for fatigue and psychological wellbeing. Practices such as yoga, through breathing exercises, adapted postures and relaxation techniques, can help with stress management and improve quality of life. These are complementary tools to pharmacological and rehabilitative therapies, to be incorporated into a holistic approach to health that also takes into account diet, emotional well-being and social relationships.

Vita SMisurata: sharing becomes part of the treatment journey

Alongside therapeutic innovation, it is increasingly important to provide people with multiple sclerosis with the tools they need to cope with everyday challenges, access scientifically reliable information and connect with others going through similar experiences. Sharing experiences and exchanging views can help combat feelings of isolation and empower people to take control of their own health.

It is within this context that ‘Vita SMisurata’ is situated – a project promoted by Merck Italia with the support and collaboration of AISM (the Italian Multiple Sclerosis Association) and SIN (the Italian Society of Neurology). A digital platform that connects people with multiple sclerosis and their carers, bringing together scientific content, personal accounts and practical advice on coping with the various aspects of daily life. From mental and physical wellbeing to nutrition and even intimacy, the project highlights aspects that often take a back seat in the clinical journey, despite having a significant impact on people’s lives. The distinctive value of Vita SMisurata lies in its peer-to-peer approach: those living with the condition are not merely recipients of information, but can actively contribute to the platform by sharing experiences, suggestions and personal accounts that become part of a shared resource. This initiative begins online and continues locally through dedicated initiatives, creating opportunities for people to meet and get involved.

It is an example of how scientific knowledge can be combined with the direct experience of those living with the condition, highlighting an essential aspect of care: listening. Because caring for people with multiple sclerosis also means understanding how the condition affects each person’s choices, relationships and aspirations.

Quality of life as the goal of future medicine

Research and therapeutic innovation will continue to be the cornerstones of progress in multiple sclerosis, but their value will increasingly need to be measured in terms of the benefits they bring to people’s lives in the real world. The ability to continue working, nurture relationships, take part in physical activity, maintain one’s independence and plan for the future must become an integral part of treatment objectives. The challenge is therefore twofold: to continue investing in research to modify the course of the disease and, at the same time, to develop care models that truly put the individual at the centre. Because today, the real ambition is not merely to live longer with multiple sclerosis, but to live better, whilst retaining the freedom to choose, plan and shape one’s own future.

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*Full Professor of Neurology at the Vita-Salute San Raffaele University and Head of the Neurology Unit, the Neurophysiology Department and the Neurorehabilitation Unit at the IRCCS San Raffaele Hospital, Milan

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