Pulse

Obesity: a pandemic affecting Italy and Spain, but the weapons to fight it are still blunted

The risk of obesity increases in Europe, new drugs and strategies could change the way we tackle this crisis

by Marzio Bartoloni (Il Sole 24 Ore), Andrea Muñoz and Fran Sánchez Becerril (El Confidencial)

Un medico misura il grasso corporeo della vita di un uomo obeso.

8' min read

8' min read

There are those who call it a new 'pandemic', for sure obesity is already a 'global epidemic' as the WHO has renamed it: 1.9 billion people are overweight, 650 million are obese with 4 million deaths a year as a consequence of this condition that triggers chronic diseases such as diabetes, cardiovascular diseases and even cancer. And Italy, the first country in the world that is preparing to pass a law recognising obesity as a disease, is among the hardest hit, with one in three Italians overweight and one in ten obese, and a near future that points to the worst, given that the country that was once the standard-bearer of the Mediterranean diet - a model in the world and the first 'vaccine' against extra kilos - is second in Europe for the number of obese or overweight children.

In Spain, as many as one in two people are overweight and almost 20% are obese. But how to stop this obesity pandemic? The strategies and problems vary from country to country, even in Europe, and range from the shortage of qualified personnel in hospitals, as in Spain for example, to the number one problem of resources to pay for treatment and especially the promising new anti-obesity drugs that are flooding the market and that Italy would like to offer.

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In Italy the first law recognising obesity as a disease

Italy is preparing to become the first country in the world to pass a law recognising obesity as a real 'progressive and relapsing' disease, and those who suffer from it will be entitled to receive free treatment that will be provided for by the essential levels of care, i.e. those services that the National Health Service must guarantee to all citizens. The law, approved at the beginning of last May, could be finally passed by the summer. But the road to care for millions of patients is still a long and bumpy one: the measure consists of just a few articles, allocating modest resources needed just to set up an Observatory to study obesity and launch information and communication campaigns on the importance of prevention: this chronic disease is in fact the result of multiple factors closely linked to one another, including sedentary lifestyles and reduced physical activity, poor diet, socioeconomic determinants, psychological aspects and stress, in addition to genetic factors. And being able to intervene in time also means saving money, since it is estimated that between direct and indirect costs (related pathologies to be treated) the cost impact on the National Health Service exceeds 13 billion each year. In short, betting and investing on anti-obesity treatments could eventually pay off for everyone.

The resource node for free care

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The problem, however, is to really follow up on Article 2 of the law, which states that 'people suffering from obesity' will be able to benefit from 'the services contained in the essential levels of care (the so-called Lea) provided by the National Health Service', . This means that with the updating of the LEAs, all those anti-obesity services such as examinations and analyses, the new drugs that have been gaining ground in recent years, up to bariatric surgery and medical indications on lifestyles such as the medical prescription of sporting activity, will have to be included among the free treatments (or against payment of the ticket).

"After the passing of this law, there is no going back. It is like when the treatment of diabetes became part of the essential levels of care. Now the resources must be found, centres identified, and therapies defined. And it must be done because the cost of obesity is such that any intelligent state had better get it treated before it becomes a problem,' Andrea Lenzi, an endocrinologist and one of the leading experts on the subject in Italy, explained to Il Sole 24 Ore, to the extent that he collaborated in drafting the law. 'Treatment,' Lenzi goes on to explain, 'will not concern those who are overweight, nor all six million obese people in Italy. There will be specific guidelines and indicators to identify who is entitled to it with precise paths: an obese person will first go to the family doctor who, in the event of complications, will refer him or her to a specialised outpatient clinic on the territory, which in turn can send him or her to the regional specialised centre that will produce a complete diagnosis and a treatment plan that may last several months'.

The British model for promising anti-obesity drugs

The other momentous step could be the free prescription of the new anti-obesity drugs. A delegation from the Italian Medicines Agency (Aifa) flew to England in recent days to study the path already taken by London on the war against obesity: in particular, Aifa is trying to understand how and whether to replicate the English model in Italy too, not least because the National health service is very similar in its operation to our SSN.

At the moment, in fact, the British Health Service has recommended through Nice (the National Institute for health and care excellence) the reimbursability of a drug for obesity in adult patients in which certain specific requirements are met: very advanced obesity (second degree obesity with a body mass index -BMI- greater than or equal to 35 kg/m²) and at least one other major weight-related pathology (type 2 diabetes, hypertension, cardiovascular disorders).

These requirements restrict the potential pool of beneficiaries. Its prescription is then envisaged in combination with a low-calorie diet and increased physical activity, while its reimbursability is conditional on achieving a weight loss of at least 5 per cent or more within six months. Otherwise, continuation of therapy is assessed on the basis of the benefit-risk balance for the patient.

New drugs will become widely consumed

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In England, a study has also started on the possible reduction of direct and indirect public health expenditure in the medium to long term: under the lens will end up not only the direct effects on health but also the consequences both in social life (inactivity, limitations) and at work by measuring them, for example, on the basis of absences from work or disability. This is a study that could be replicated in Italy, with Lombardy leading the way. 'As soon as the treatment of obesity is included among the essential levels of care, with the approval of the law, the AIFA, through the Scientific and Economic Commission, will evaluate the possible reimbursability of the new drugs that are arriving, taking inspiration from existing models. That is why we went on a mission to England,' the president of the Italian Medicines Agency, Robert Nisticò, confirmed to Il Sole 24 Ore. The problem is not so much the price, but the fact that it affects millions of people and therefore must be provided according to strict criteria and to those who really need it. However, it must be said that not treating obesity leads to major consequences such as diabetes, cardiovascular risk, and cancer. All pathologies with a major social and economic impact. Prices, however,' the Aifa chairman concludes, 'will go down and then drugs that are injectable today will become oral and will therefore be increasingly widely consumed'.

The Spanish case

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In Spain, there are not enough nutritionists in public hospitals. Very few autonomous communities include the figure of the dietitian-nutritionist in their public hospitals. Furthermore, some nutrition units do not even include this professional figure. Why is it so difficult to find a dietitian-nutritionist in a public hospital in Spain?

'Due to a lack of political will, because there is overwhelming evidence of the benefits they bring'. Luis J. Morán Fagúndez, president of the General Council of Official Orders of Dietitians-Nutritionists (CGCODN), explains the situation of his profession in Spain in this way. With the exception of some regions, such as Galicia, which integrated 94 professionals into its primary care system in 2022, or Catalonia, where the figure exists, dietitian-nutritionists (DN) are practically absent in many public hospitals.

"In the regions where they exist, there are very few," the president adds. "This is a cost-saving measure that would not lead to additional expenditure for the public health system. It does not make sense and we do not understand it. Besides, the current demand for nutritional services is met by other professionals who do their best to cover this sector,' Morán says. For example, in the case of Andalusia, a region that Morán knows well as a board member of the Andalusian Society of Clinical Nutrition and Dietetics (SANCYD), there have been nutrition units in hospitals for more than 30 years: 'They are composed of dietician technicians, endocrinologists, nursing assistants or food scientists, but not DN. These professionals also demand our presence'.

Another point raised by the expert is the inequality this situation creates: 'Since there are no DN in public healthcare, if a patient needs these services, they have to pay for them privately. For people with lower incomes, who have the highest rates of childhood and adult obesity, this is impossible. It is a vicious circle'.

In Spain, 55.8 per cent of the population is overweight and 18.7 per cent obese, according to data from a study by the Instituto de Salud Carlos III (ISCIII) and the Spanish Agency for Food Safety and Nutrition (AESAN). The study, published in October 2023, also concluded that overweight and obesity in adults is more common among people and population groups with lower levels of education, or living in smaller cities and areas with lower income levels. "We are seeing a continued increase in rates, even in projections for 2050. If obesity continues to increase, it will lead to a serious public health problem as associated diseases, such as diabetes or various types of cancer, become more common. This will create a burden that the National Health System (NHS) will find difficult to manage,' warns the nutritionist.

"A paradigm shift is taking place in the way we understand how best to tackle obesity and its comorbidities: by treating the root cause of all the negative outcomes caused by this disease," Albert Lecube Torelló, vice-president of the Spanish Society for the Study of Obesity (SEEDO), tells this newspaper. The 'Obesity First' movement is based on decades of research linking excess weight to more than 200 health problems, such as heart failure, premature death and even 13 types of cancer. And its impact is not limited to the most serious diseases, but also plays an important role in conditions such as type 2 diabetes, which affects 15% of Spaniards, almost 9 out of 10 of whom have excess body fat.

'It is not a question of stopping treating diseases in which obesity plays a role, such as diabetes, cardiovascular hypertension or dyslipidaemia, but rather of increasingly recognising the need to treat the cause of the complications [obesity itself],' says Lecube, who is head of the Department of Endocrinology and Nutrition at the Arnau de Vilanova University Hospital in Lleida.

Interministerial Committee

In 2024, the Spanish Council of Ministers approved the creation of the Interministerial Committee for the Reduction of Childhood Obesity. This new body, led by the Ministry of Health and composed of representatives from 18 ministries, will be responsible for guiding and coordinating the National Strategic Plan for Reducing Childhood Obesity 2022-2030. According to the government, the plan includes 200 measures to improve the health and well-being of children and adolescents, addressing various social, legislative and communication aspects. The Committee's main functions include promoting the integration of the plan's strategies into public policy, ensuring consistency between sectoral initiatives, coordinating with regional and local governments, and overseeing communication strategies.

The Committee will also monitor and evaluate the impact of the plan using pre-established indicators. Childhood obesity is a serious public health problem in Spain, mainly affecting children from low-income families. According to a 2023 report based on 2020 data, 30% of children between the ages of 2 and 17 were overweight and 10% were obese.

*This article is part of the European collaborative journalism project 'Pulse'

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